human CHRD shRNA silencing AAV

Cat. No: shAAV-205187

Availability: 6-8 weeks

Name: AAV-h-CHRD-shRNA

This is an AAV expressing shRNA for silencing of Human CHRD.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CHRD
Gene Name: chordin
Gene ID: 8646
ORF Size: 2868 bp
RefSeq#: NM_003741
Gene Description: CHRD encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined.
UniGene ID: Hs.166186
HGNC ID: HGNC:1949