human CH25H shRNA silencing AAV

Cat. No: shAAV-205084

Availability: 6-8 weeks

Name: AAV-h-CH25H-shRNA

This is an AAV expressing shRNA for silencing of Human CH25H.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CH25H
Gene Name: cholesterol 25-hydroxylase
Gene ID: 9023
Gene Synonyms: C25H
ORF Size: 819 bp
RefSeq#: NM_003956
Gene Description: This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.
UniGene ID: Hs.47357
HGNC ID: HGNC:1907