human CGNL1 shRNA silencing AAV

Cat. No: shAAV-205079

Availability: 6-8 weeks

Name: AAV-h-CGNL1-shRNA

This is an AAV expressing shRNA for silencing of Human CGNL1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CGNL1
Gene Name: cingulin like 1
Gene ID: 84952
Gene Synonyms: JACOP; PCING
ORF Size: 3909 bp
RefSeq#: NM_032866
Gene Description: CGNL1 encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene.
UniGene ID: Hs.148989
HGNC ID: HGNC:25931