human CFLAR shRNA silencing AAV

Cat. No: shAAV-205056

Availability: 4-5 weeks

Name: AAV-h-CFLAR-shRNA

This is an AAV expressing shRNA for silencing of Human CFLAR.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CFLAR
Gene Name: CASP8 and FADD like apoptosis regulator
Gene ID: 8837
Gene Synonyms: c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; CLARP; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT
ORF Size: 1443 bp
RefSeq#: NM_003879
Gene Description: CFLAR is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
UniGene ID: Hs.390736
HGNC ID: HGNC:1876