human EFEMP2 shRNA silencing AAV

Cat. No: shAAV-205052

Availability: 4-5 weeks

Name: AAV-h-EFEMP2-shRNA

This is an AAV expressing shRNA for silencing of Human EFEMP2.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EFEMP2
Gene Name: EGF containing fibulin like extracellular matrix protein 2
Gene ID: 30008
Gene Synonyms: ARCL1B; FBLN4; MBP1; UPH1
ORF Size: 1332 bp
RefSeq#: NM_016938
Gene Description: A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene.
UniGene ID: Hs.170622
HGNC ID: HGNC:3219