human CFC1 shRNA silencing AAV

Cat. No: shAAV-205037

Availability: 6-8 weeks

Name: AAV-h-CFC1-shRNA

This is an AAV expressing shRNA for silencing of Human CFC1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CFC1
Gene Name: cripto, FRL-1, cryptic family 1
Gene ID: 55997
Gene Synonyms: CFC1B; CRYPTIC; DTGA2; HTX2
ORF Size: 672 bp
RefSeq#: NM_032545
Gene Description: CFC1 encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniGene ID: Hs.595719
HGNC ID: HGNC:18292