human CEBPB shRNA silencing AAV

Cat. No: shAAV-204936

Availability: 4-5 weeks

Name: AAV-h-CEBPB-shRNA

This is an AAV expressing shRNA for silencing of Human CEBPB.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CEBPB
Gene Name: CCAAT/enhancer binding protein beta
Gene ID: 1051
Gene Synonyms: C/EBP-beta; IL6DBP; NF-IL6; TCF5
ORF Size: 1038 bp
RefSeq#: NM_005194
Gene Description: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
UniGene ID: Hs.701858
HGNC ID: HGNC:1834