human CDK9 shRNA silencing AAV

Cat. No: shAAV-204866

Availability: 4-5 weeks

Name: AAV-h-CDK9-shRNA

This is an AAV expressing shRNA for silencing of Human CDK9.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CDK9
Gene Name: cyclin dependent kinase 9
Gene ID: 1025
Gene Synonyms: C-2k; CDC2L4; CTK1; PITALRE; TAK
ORF Size: 1119 bp
RefSeq#: NM_001261
Gene Description: CDK9 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
UniGene ID: Hs.706809
HGNC ID: HGNC:1780