human CDK5RAP2 shRNA silencing AAV

Cat. No: shAAV-204856

Availability: 6-8 weeks

Name: AAV-h-CDK5RAP2-shRNA

This is an AAV expressing shRNA for silencing of Human CDK5RAP2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CDK5RAP2
Gene Name: CDK5 regulatory subunit associated protein 2
Gene ID: 55755
Gene Synonyms: C48; Cep215; MCPH3
ORF Size: 5679 bp
RefSeq#: NM_018249
Gene Description: Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein may also be a substrate of neuronal CDC2-like kinase. Multiple transcript variants exist for this gene, but the full-length nature of only two has been determined.
UniGene ID: Hs.269560
HGNC ID: HGNC:18672