human CDH20 shRNA silencing AAV

Cat. No: shAAV-204815

Availability: 6-8 weeks

Name: AAV-h-CDH20-shRNA

This is an AAV expressing shRNA for silencing of Human CDH20.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CDH20
Gene Name: cadherin 20
Gene ID: 28316
Gene Synonyms: Cdh7; CDH7L3
ORF Size: 2406 bp
RefSeq#: NM_031891
Gene Description: CDH20 is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
UniGene ID: Hs.671510
HGNC ID: HGNC:1760