human CDH17 shRNA silencing AAV

Cat. No: shAAV-204810

Availability: 4-5 weeks

Name: AAV-h-CDH17-shRNA

This is an AAV expressing shRNA for silencing of Human CDH17.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CDH17
Gene Name: cadherin 17
Gene ID: 1015
Gene Synonyms: CDH16; HPT-1; HPT1
ORF Size: 2499 bp
RefSeq#: NM_004063
Gene Description: CDH17 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.591853
HGNC ID: HGNC:1756