human CDC42BPB shRNA silencing AAV

Cat. No: shAAV-204762

Availability: 4-5 weeks

Name: AAV-h-CDC42BPB-shRNA

This is an AAV expressing shRNA for silencing of Human CDC42BPB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CDC42BPB
Gene Name: CDC42 binding protein kinase beta
Gene ID: 9578
Gene Synonyms: MRCKB
ORF Size: 5136 bp
RefSeq#: NM_006035
Gene Description: CDC42BPB encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization.
UniGene ID: Hs.654634
HGNC ID: HGNC:1738