human CDA shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-204709
Availability:
4-5 weeks
Name:
AAV-h-CDA-shRNA
This is an AAV expressing shRNA for silencing of Human CDA.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- CDA
- Gene Name
- cytidine deaminase
- Gene ID
- 978
- Gene Synonyms
- CDD
- ORF Size
- 441 bp
- RefSeq#
- NM_001785
- Gene Description
- CDA encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
- UniGene ID
- Hs.466910
- HGNC ID
- HGNC:1712
Related Products
Product | Cat No. |
---|---|
AAV-h-CDA | AAV-204709 |
AAV-m-CDA | AAV-255065 |
Ad-h-CDA | ADV-204709 |
Ad-m-CDA | ADV-255065 |
AAV-m-CDA-shRNA | shAAV-255065 |
Ad-h-CDA-shRNA | shADV-204709 |
Ad-m-CDA-shRNA | shADV-255065 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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