human CCL8 shRNA silencing AAV

Cat. No: shAAV-204468

Availability: 6-8 weeks

Name: AAV-h-CCL8-shRNA

This is an AAV expressing shRNA for silencing of Human CCL8.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CCL8
Gene Name: C-C motif chemokine ligand 8
Gene ID: 6355
Gene Synonyms: HC14; MCP-2; MCP2; SCYA10; SCYA8
ORF Size: 300 bp
RefSeq#: NM_005623
Gene Description: CCL8 is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
UniGene ID: Hs.271387
HGNC ID: HGNC:10635