human CCDC40 shRNA silencing AAV

Cat. No: shAAV-204317

Availability: 6-8 weeks

Name: AAV-h-CCDC40-shRNA

This is an AAV expressing shRNA for silencing of Human CCDC40.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CCDC40
Gene Name: coiled-coil domain containing 40
Gene ID: 55036
Gene Synonyms: CILD15; FAP172
ORF Size: 3096 bp
RefSeq#: NM_017950
Gene Description: CCDC40 encodes a protein that is necessary for motile cilia function. It functions in correct left-right axis formation by regulating the assembly of the inner dynein arm and the dynein regulatory complexes, which control ciliary beat. Mutations in this gene cause ciliary dyskinesia type 15, a disorder due to defects in cilia motility. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.202542
HGNC ID: HGNC:26090