human CALR3 shRNA silencing AAV

Cat. No: shAAV-203989

Availability: 6-8 weeks

Name: AAV-h-CALR3-shRNA

This is an AAV expressing shRNA for silencing of Human CALR3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CALR3
Gene Name: calreticulin 3
Gene ID: 125972
Gene Synonyms: CMH19; CRT2; CT93
ORF Size: 1155 bp
RefSeq#: NM_145046
Gene Description: CALR3 belongs to the calreticulin family, members of which are calcium-binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy.
UniGene ID: Hs.304020
HGNC ID: HGNC:20407