human CALCR shRNA silencing AAV

Cat. No: shAAV-203962

Availability: 6-8 weeks

Name: AAV-h-CALCR-shRNA

This is an AAV expressing shRNA for silencing of Human CALCR.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CALCR
Gene Name: calcitonin receptor
Gene ID: 799
Gene Synonyms: CRT; CT-R; CTR; CTR1
ORF Size: 1425 bp
RefSeq#: NM_001742
Gene Description: CALCR encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.489127
HGNC ID: HGNC:1440