human CABC1 shRNA silencing AAV

Cat. No: shAAV-203890

Availability: 4-5 weeks

Name: AAV-h-CABC1-shRNA

This is an AAV expressing shRNA for silencing of Human COQ8A.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: COQ8A
Gene Name: coenzyme Q8A
Gene ID: 56997
Gene Synonyms: ADCK3; ARCA2; CABC1; COQ10D4; COQ8; SCAR9
ORF Size: 1944 bp
RefSeq#: NM_020247
Gene Description: ADCK3 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.
UniGene ID: Hs.118241
HGNC ID: HGNC:16812