human C9ORF95 shRNA silencing AAV

Cat. No: shAAV-203857

Availability: 4-5 weeks

Name: AAV-h-C9ORF95-shRNA

This is an AAV expressing shRNA for silencing of Human NMRK1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NMRK1
Gene Name: nicotinamide riboside kinase 1
Gene ID: 54981
Gene Synonyms: bA235O14.2; C9orf95; NRK1
ORF Size: 528 bp
RefSeq#: NM_017881
Gene Description: Nicotinamide adenine dinucleotide (NAD+) is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADP-ribosyl groups used in various reactions. Nicotinic acid and nicotinamide, collectively known as niacin, are the vitamin precursors of NAD+. Nicotinamide riboside kinases, such as NRK1, function to synthesize NAD+ through nicotinamide mononucleotide using nicotinamide riboside as the precursor (Bieganowski and Brenner, 2004 (PubMed 15137942)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.494186
HGNC ID: HGNC:26057