human C8B shRNA silencing AAV

Cat. No: shAAV-203713

Availability: 6-8 weeks

Name: AAV-h-C8B-shRNA

This is an AAV expressing shRNA for silencing of Human C8B.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: C8B
Gene Name: complement C8 beta chain
Gene ID: 732
Gene Synonyms: C82
ORF Size: 1776 bp
RefSeq#: NM_000066
Gene Description: C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.
UniGene ID: Hs.391835
HGNC ID: HGNC:1353