human C21ORF82 shRNA silencing AAV

Cat. No: shAAV-203252

Availability: 4-5 weeks

Name: AAV-h-C21ORF82-shRNA

This is an AAV expressing shRNA for silencing of Human MRPS6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MRPS6
Gene Name: mitochondrial ribosomal protein S6
Gene ID: 64968
Gene Synonyms: C21orf101; MRP-S6; RPMS6; S6mt
ORF Size: 378 bp
RefSeq#: NM_032476
Gene Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q.
UniGene ID: Hs.302742
HGNC ID: HGNC:14051