human C1QA shRNA silencing AAV

Cat. No: shAAV-203131

Availability: 6-8 weeks

Name: AAV-h-C1QA-shRNA

This is an AAV expressing shRNA for silencing of Human C1QA.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: C1QA
Gene Name: complement C1q A chain
Gene ID: 712
ORF Size: 738 bp
RefSeq#: NM_015991
Gene Description: C1QA encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QA encodes the A-chain polypeptide of human complement subcomponent C1q.
UniGene ID: Hs.632379
HGNC ID: HGNC:1241