human BRP44L shRNA silencing AAV

Cat. No: shAAV-202277

Availability: 4-5 weeks

Name: AAV-h-BRP44L-shRNA

This is an AAV expressing shRNA for silencing of Human MPC1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MPC1
Gene Name: mitochondrial pyruvate carrier 1
Gene ID: 51660
Gene Synonyms: BRP44L; CGI-129; dJ68L15.3; MPYCD
ORF Size: 330 bp
RefSeq#: NM_016098
Gene Description: MPC1 is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene.
UniGene ID: Hs.172755
HGNC ID: HGNC:21606