human BRD4 shRNA silencing AAV

Cat. No: shAAV-202257

Availability: 4-5 weeks

Name: AAV-h-BRD4-shRNA

This is an AAV expressing shRNA for silencing of Human BRD4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BRD4
Gene Name: bromodomain containing 4
Gene ID: 23476
Gene Synonyms: CAP; HUNK1; HUNKI; MCAP
ORF Size: 2385 bp
RefSeq#: NM_058243
Gene Description: BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
UniGene ID: Hs.187763
HGNC ID: HGNC:13575