human BMX shRNA silencing AAV

Cat. No: shAAV-202208

Availability: 6-8 weeks

Name: AAV-h-BMX-shRNA

This is an AAV expressing shRNA for silencing of Human BMX.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BMX
Gene Name: BMX non-receptor tyrosine kinase
Gene ID: 660
Gene Synonyms: ETK; PSCTK2; PSCTK3
ORF Size: 2028 bp
RefSeq#: NM_001721
Gene Description: BMX encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UniGene ID: Hs.495731
HGNC ID: HGNC:1079