human BLCAP shRNA silencing AAV

Cat. No: shAAV-202154

Availability: 6-8 weeks

Name: AAV-h-BLCAP-shRNA

This is an AAV expressing shRNA for silencing of Human BLCAP.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BLCAP
Gene Name: bladder cancer associated protein
Gene ID: 10904
Gene Synonyms: BC10
ORF Size: 264 bp
RefSeq#: NM_006698
Gene Description: BLCAP encodes a tumor suppressor protein that reduces cell growth by stimulating apoptosis. The first intron of this gene contains the neuronatin gene, which is imprinted and only expressed from the paternal allele. BLCAP is imprinted in brain where it is differentially expressed from different promoters. Transcription from the upstream promoter occurs preferentially on the maternal allele, and transcripts are preferentially expressed from the downstream promoter on the paternal allele. Alternative promoters and alternative splicing result in multiple transcript variants that encode the same protein.
UniGene ID: Hs.718404
HGNC ID: HGNC:1055