human BIRC3 shRNA silencing AAV

Cat. No: shAAV-202147

Availability: 4-5 weeks

Name: AAV-h-BIRC3-shRNA

This is an AAV expressing shRNA for silencing of Human BIRC3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BIRC3
Gene Name: baculoviral IAP repeat containing 3
Gene ID: 330
Gene Synonyms: AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49
ORF Size: 1815 bp
RefSeq#: NM_001165
Gene Description: BIRC3 encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
UniGene ID: Hs.127799
HGNC ID: HGNC:591