human BIRC2 shRNA silencing AAV

Cat. No: shAAV-202145

Availability: 4-5 weeks

Name: AAV-h-BIRC2-shRNA

This is an AAV expressing shRNA for silencing of Human BIRC2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BIRC2
Gene Name: baculoviral IAP repeat containing 2
Gene ID: 329
Gene Synonyms: API1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
ORF Size: 1857 bp
RefSeq#: NM_001166
Gene Description: BIRC2 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.696238
HGNC ID: HGNC:590