human BHLHE22 shRNA silencing AAV

Cat. No: shAAV-202127

Availability: 6-8 weeks

Name: AAV-h-BHLHE22-shRNA

This is an AAV expressing shRNA for silencing of Human BHLHE22.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BHLHE22
Gene Name: basic helix-loop-helix family member e22
Gene ID: 27319
Gene Synonyms: Beta3; Beta3a; BHLHB5; CAGL85; TNRC20
ORF Size: 1146 bp
RefSeq#: NM_152414
Gene Description: BHLHE22 belongs to the basic helix-loop-helix (bHLH) family of transcription factors that regulate cell fate determination, proliferation, and differentiation. These proteins function as dimers and bind to an E-box DNA sequence (CANNTG). BHLHE22 is expressed exclusively in the central nervous system and retina (Xu et al., 2002 (PubMed 12213201)).(supplied by OMIM, Jul 2010)
UniGene ID: Hs.591870
HGNC ID: HGNC:11963