human BDNF shRNA silencing AAV

Cat. No: shAAV-202083

Availability: 4-5 weeks

Name: AAV-h-BDNF-shRNA

This is an AAV expressing shRNA for silencing of Human BDNF.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BDNF
Gene Name: brain derived neurotrophic factor
Gene ID: 627
Gene Synonyms: ANON2; BULN2
ORF Size: 744 bp
RefSeq#: NM_001709
Gene Description: BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene.
UniGene ID: Hs.502182
HGNC ID: HGNC:1033