human AVPR1B shRNA silencing AAV

Cat. No: shAAV-201848

Availability: 6-8 weeks

Name: AAV-h-AVPR1B-shRNA

This is an AAV expressing shRNA for silencing of Human AVPR1B.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AVPR1B
Gene Name: arginine vasopressin receptor 1B
Gene ID: 553
Gene Synonyms: AVPR3
ORF Size: 1275 bp
RefSeq#: NM_000707
Gene Description: AVPR1B acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
UniGene ID: Hs.1372
HGNC ID: HGNC:896