human AURKA shRNA silencing AAV

Cat. No: shAAV-201827

Availability: 4-5 weeks

Name: AAV-h-AURKA-shRNA

This is an AAV expressing shRNA for silencing of Human AURKA.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AURKA
Gene Name: aurora kinase A
Gene ID: 6790
Gene Synonyms: AIK; ARK1; AURA; BTAK; PPP1R47; STK15; STK6; STK7
ORF Size: 1212 bp
RefSeq#: NM_003600
Gene Description: AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.250822
HGNC ID: HGNC:11393