human ATP1B4 shRNA silencing AAV

Cat. No: shAAV-201689

Availability: 6-8 weeks

Name: AAV-h-ATP1B4-shRNA

This is an AAV expressing shRNA for silencing of Human ATP1B4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ATP1B4
Gene Name: ATPase Na+/K+ transporting family member beta 4
Gene ID: 23439
ORF Size: 945 bp
RefSeq#: NM_012069
Gene Description: ATP1B4 has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.662608