human ARSB shRNA silencing AAV

Cat. No: shAAV-201485

Availability: 4-5 weeks

Name: AAV-h-ARSB-shRNA

This is an AAV expressing shRNA for silencing of Human ARSB.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ARSB
Gene Name: arylsulfatase B
Gene ID: 411
Gene Synonyms: ASB; G4S; MPS6
ORF Size: 1242 bp
RefSeq#: NM_000046
Gene Description: Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targetted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
UniGene ID: Hs.604199
HGNC ID: HGNC:714