human ARMC10 shRNA silencing AAV

Cat. No: shAAV-201427

Availability: 4-5 weeks

Name: AAV-h-ARMC10-shRNA

This is an AAV expressing shRNA for silencing of Human ARMC10.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ARMC10
Gene Name: armadillo repeat containing 10
Gene ID: 83787
Gene Synonyms: PNAS-112; PNAS112; PSEC0198; SVH
ORF Size: 927 bp
RefSeq#: NM_031905
Gene Description: ARMC10 encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
UniGene ID: Hs.287412
HGNC ID: HGNC:21706