human ARID5B shRNA silencing AAV

Cat. No: shAAV-201386

Availability: 4-5 weeks

Name: AAV-h-ARID5B-shRNA

This is an AAV expressing shRNA for silencing of Human ARID5B.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ARID5B
Gene Name: AT-rich interaction domain 5B
Gene ID: 84159
Gene Synonyms: DESRT; MRF-2; MRF2
ORF Size: 3564 bp
RefSeq#: NM_032199
Gene Description: ARID5B encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. ARID5B also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniGene ID: Hs.535297
HGNC ID: HGNC:17362