human APTX shRNA silencing AAV

Cat. No: shAAV-201227

Availability: 4-5 weeks

Name: AAV-h-APTX-shRNA

This is an AAV expressing shRNA for silencing of Human APTX.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: APTX
Gene Name: aprataxin
Gene ID: 54840
Gene Synonyms: AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT
ORF Size: 765 bp
RefSeq#: NM_001195254
Gene Description: APTX encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.
UniGene ID: Hs.20158
HGNC ID: HGNC:15984