human APOA1 shRNA silencing AAV

Cat. No: shAAV-201161

Availability: 6-8 weeks

Name: AAV-h-APOA1-shRNA

This is an AAV expressing shRNA for silencing of Human APOA1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: APOA1
Gene Name: apolipoprotein A1
Gene ID: 335
Gene Synonyms: apo(a)
ORF Size: 804 bp
RefSeq#: NM_000039
Gene Description: APOA1 encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. APOA1 is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
UniGene ID: Hs.633003
HGNC ID: HGNC:600