human AP4B1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-201108
Availability:
4-5 weeks
Name:
AAV-h-AP4B1-shRNA
This is an AAV expressing shRNA for silencing of Human AP4B1.
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Product Info
- Knockdown
- >60% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- AP4B1
- Gene Name
- adaptor related protein complex 4 beta 1 subunit
- Gene ID
- 10717
- Gene Synonyms
- BETA-4; CPSQ5; SPG47
- ORF Size
- 2220 bp
- RefSeq#
- NM_006594
- Gene Description
- AP4B1 encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.515048
- HGNC ID
- HGNC:572
Related Products
Product | Cat No. |
---|---|
AAV-h-AP4B1 | AAV-201108 |
AAV-m-AP4B1 | AAV-280547 |
Ad-h-AP4B1 | ADV-201108 |
Ad-m-AP4B1 | ADV-280547 |
AAV-m-AP4B1-shRNA | shAAV-280547 |
Ad-h-AP4B1-shRNA | shADV-201108 |
Ad-m-AP4B1-shRNA | shADV-280547 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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