human AP2A1 shRNA silencing AAV

Cat. No: shAAV-201089

Availability: 4-5 weeks

Name: AAV-h-AP2A1-shRNA

This is an AAV expressing shRNA for silencing of Human AP2A1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AP2A1
Gene Name: adaptor related protein complex 2 alpha 1 subunit
Gene ID: 160
Gene Synonyms: ADTAA; AP2-ALPHA; CLAPA1
ORF Size: 2949 bp
RefSeq#: NM_014203
Gene Description: AP2A1 encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.
UniGene ID: Hs.467125
HGNC ID: HGNC:561