human AMOT shRNA silencing AAV

Cat. No: shAAV-200865

Availability: 4-5 weeks

Name: AAV-h-AMOT-shRNA

This is an AAV expressing shRNA for silencing of Human AMOT.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AMOT
Gene Name: angiomotin
Gene ID: 154796
ORF Size: 2031 bp
RefSeq#: NM_133265
Gene Description: AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniGene ID: Hs.528051
HGNC ID: HGNC:17810