human AKT3 shRNA silencing AAV

Cat. No: shAAV-200709

Availability: 4-5 weeks

Name: AAV-h-AKT3-shRNA

This is an AAV expressing shRNA for silencing of Human AKT3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AKT3
Gene Name: AKT serine/threonine kinase 3
Gene ID: 10000
Gene Synonyms: MPPH; MPPH2; PKB-GAMMA; PKBG; PRKBG; RAC-gamma; RAC-PK-gamma; STK-2
ORF Size: 1398 bp
RefSeq#: NM_005465
Gene Description: AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.
UniGene ID: Hs.498292
HGNC ID: HGNC:393