human AKAP8 shRNA silencing AAV

Cat. No: shAAV-200666

Availability: 4-5 weeks

Name: AAV-h-AKAP8-shRNA

This is an AAV expressing shRNA for silencing of Human AKAP8.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AKAP8
Gene Name: A-kinase anchoring protein 8
Gene ID: 10270
Gene Synonyms: AKAP 95; AKAP-8; AKAP-95; AKAP95
ORF Size: 2079 bp
RefSeq#: NM_005858
Gene Description: AKAP8 encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. AKAP8 encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.
UniGene ID: Hs.594496
HGNC ID: HGNC:378