human AGAP2 shRNA silencing AAV

Cat. No: shAAV-200547

Availability: 4-5 weeks

Name: AAV-h-AGAP2-shRNA

This is an AAV expressing shRNA for silencing of Human AGAP2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AGAP2
Gene Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Gene ID: 116986
Gene Synonyms: CENTG1; GGAP2; PIKE
ORF Size: 2511 bp
RefSeq#: NM_014770
Gene Description: AGAP2 belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
UniGene ID: Hs.632854
HGNC ID: HGNC:16921