human AFF2 shRNA silencing AAV

Cat. No: shAAV-200533

Availability: 6-8 weeks

Name: AAV-h-AFF2-shRNA

This is an AAV expressing shRNA for silencing of Human AFF2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AFF2
Gene Name: AF4/FMR2 family member 2
Gene ID: 2334
Gene Synonyms: FMR2; FMR2P; FRAXE; MRX2; OX19
ORF Size: 3906 bp
RefSeq#: NM_002025
Gene Description: AFF2 encodes a putative transcriptional activator that is a member of the AF4\FMR2 gene family. AFF2 is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.496911
HGNC ID: HGNC:3776