human ADNP shRNA silencing AAV

Cat. No: shAAV-200481

Availability: 4-5 weeks

Name: AAV-h-ADNP-shRNA

This is an AAV expressing shRNA for silencing of Human ADNP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ADNP
Gene Name: activity dependent neuroprotector homeobox
Gene ID: 23394
Gene Synonyms: ADNP1; HVDAS; MRD28
ORF Size: 3309 bp
RefSeq#: NM_015339
Gene Description: Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
UniGene ID: Hs.570355
HGNC ID: HGNC:15766