human ADAR shRNA silencing AAV

Cat. No: shAAV-200406

Availability: 4-5 weeks

Name: AAV-h-ADAR-shRNA

This is an AAV expressing shRNA for silencing of Human ADAR.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ADAR
Gene Name: adenosine deaminase, RNA specific
Gene ID: 103
Gene Synonyms: ADAR1; AGS6; DRADA; DSH; DSRAD; G1P1; IFI-4; IFI4; K88DSRBP; P136
ORF Size: 3681 bp
RefSeq#: NM_001111
Gene Description: ADAR encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.12341
HGNC ID: HGNC:225