human ADAM12 shRNA silencing AAV

Cat. No: shAAV-200347

Availability: 4-5 weeks

Name: AAV-h-ADAM12-shRNA

This is an AAV expressing shRNA for silencing of Human ADAM12.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ADAM12
Gene Name: ADAM metallopeptidase domain 12
Gene ID: 8038
Gene Synonyms: ADAM12-OT1; CAR10; MCMP; MCMPMltna; MLTN; MLTNA
ORF Size: 2214 bp
RefSeq#: NM_003474
Gene Description: ADAM12 encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM12 has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.
UniGene ID: Hs.594537
HGNC ID: HGNC:190