human ACSS2 shRNA silencing AAV

Cat. No: shAAV-200264

Availability: 4-5 weeks

Name: AAV-h-ACSS2-shRNA

This is an AAV expressing shRNA for silencing of Human ACSS2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ACSS2
Gene Name: acyl-CoA synthetase short-chain family member 2
Gene ID: 55902
Gene Synonyms: ACAS2; ACECS; ACS; ACSA; dJ1161H23.1
ORF Size: 2106 bp
RefSeq#: NM_018677
Gene Description: ACSS2 encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.517034
HGNC ID: HGNC:15814