human ACSL6 shRNA silencing AAV

Cat. No: shAAV-200253

Availability: 6-8 weeks

Name: AAV-h-ACSL6-shRNA

This is an AAV expressing shRNA for silencing of Human ACSL6.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ACSL6
Gene Name: acyl-CoA synthetase long-chain family member 6
Gene ID: 23305
Gene Synonyms: ACS2; FACL6; LACS 6; LACS2; LACS5
ORF Size: 1821 bp
RefSeq#: NM_015256
Gene Description: ACSL6 catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.14945
HGNC ID: HGNC:16496